Regenerate & Restore
Regenerate & Restore is Ascend’s regenerative recovery program.
Designed to recalibrate the nervous system, restore cellular energy, and counteract the early biological effects of chronic stress, this program is ideal for high-performing individuals.
6 nights
Testing :
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In depth blood work check
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DNA test
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DEXA scan
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Thyroïd ultrasound
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Gut micbrobiome analysis
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Mitochondrial activity test
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Resting metabolic rate
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3D body scan
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Posture analysis
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Cognitive test
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Mental wellbeing assessment
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Nutrition habit assessment
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Sleep assessment
Therapies :
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Infrared light session
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Sauna
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Breathing session
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Customized PT session
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Cryotherapy
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Hyperbaric Oxygen Chamber Therapy
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Hypnotherapy session
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Meditation protocol
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Audiotherapy session
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Body treatment at Guerlain Spa
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Yoga session
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Personalised nutrition plan
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Herbal infusions
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Designed for individuals who operate under sustained pressure, Regenerate & Restore is created for leaders, entrepreneurs, creatives, and elite performers who understand that longevity is not achieved through endurance alone, but through intelligent recovery.
This program is for those who recognise early signs of depletion and choose to intervene by restoring nervous system balance, cellular energy, and metabolic resilience.
Beyond immediate renewal, it lays the biological foundations for long-term vitality, allowing performance, clarity, and health to be sustained well into the future.

Longevity Programs Crafted for the World’s Most Discerning Guests
Every Ascend program is a guided journey across diagnostics, regeneration, and transformation — designed to extend vitality, enhance performance, and unlock the full potential of your health.
A New Era of Longevity Travel
Ascend brings together clinical precision, regenerative medicine, and refined hospitality to redefine what a wellness program can be.
Whether your goal is metabolic reset, cognitive mastery, cellular regeneration, or peak performance, each program is built around your biology, interpreted by our longevity specialists, and delivered within the serene embrace of One&Only Aesthesis Athens.
Our Four Signature Programs
Tailored Pathways Toward a Longer, Fuller Life
Optimal Weight & Metabolic Reset
Optimal Weight & Metabolic Reset is Ascend’s science-led approach to metabolic realignment.
Far beyond a conventional detox, this program targets the biological mechanisms behind weight regulation, inflammation, and energy production.
The result is not only visible change, but a sustainable reset that supports long-term health, vitality, and metabolic longevity.
6 - 9 nights
Testing :
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DNA test
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DEXA scan
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Gut micbrobiome analysis
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Continuous glucose monitoring
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VO2 max test
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Resting metabolic rate
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3D body scan
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Posture analysis
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Nutrition habit assessment
Therapies :
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Infrared light session
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Sauna
-
Breathing session
-
Customized PT session
-
Cryotherapy
-
Exercise with Oxygen Therapy
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Altitude training
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Meditation protocol
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Probiotic cure
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Personalised nutrition plan
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Herbal infusions
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This program is designed for individuals seeking clarity and control over their metabolic health. It is ideal for those experiencing persistent fatigue, weight resistance, inflammatory symptoms, or energy fluctuations — and who wish to address these issues at their biological root.
Optimal Weight & Metabolic Reset is for guests who value a scientific, personalised approach to body composition and energy management, and who seek results that extend beyond short-term weight loss toward lasting metabolic resilience and long-term vitality.
Peak Performance & Cognitive Upgrade
Peak Performance & Cognitive Upgrade is Ascend’s advanced optimisation program for the mind and body.
Designed to elevate cognitive clarity, physical capacity, and decision-making under pressure, this program combines precision diagnostics with targeted performance and neuro-optimisation therapies.
By enhancing oxygen efficiency, nervous system balance, and mental resilience, it supports not only immediate performance gains, but the long-term preservation of cognitive and physiological excellence.
6-9 nights
Testing :
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In depth blood work check
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In depth blood pressure
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DNA test
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DEXA scan
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Mitochondrial activity test
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VO2 max
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Resting metabolic rate
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GAIT/biomecanical analysis
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3D body scan
-
Posture analysis
-
Cognitive test
-
Mental wellbeing assessment
-
Nutrition habit assessment
-
Sleep assessment
Therapies :
-
Infrared light session
-
Sauna
-
Breathing session
-
Customized PT session
-
Exercise with Oxygen therapy
-
Altitude Training
-
Cryotherapy
-
Hyperbaric Oxygen Chamber Therapy
-
Hypnotherapy session
-
Mental health coaching session
-
Meditation protocol
-
Audiotherapy session
-
Body treatment at Guerlain Spa
-
Personalised nutrition plan
-
Herbal infusions
-
This program is created for individuals whose performance defines their impact. It is ideal for CEOs, fund managers, athletes, creatives, and high-level decision-makers who rely on sustained focus, clarity, and adaptability in demanding environments.
Peak Performance & Cognitive Upgrade is for those who seek to refine their edge responsibly — optimising performance today while safeguarding cognitive function, energy, and resilience for the years ahead.
Advanced Longevity Immersion
Advanced Longevity Immersion is Ascend’s most comprehensive longevity program.
A deep, integrative journey designed to slow biological aging and strengthen the body at both cellular and systemic levels awaits you.
This program addresses the fundamental mechanisms of aging.
The objective is not only rejuvenation, but the long-term preservation of vitality, resilience, and physiological function — extending healthspan with precision and intention.
9 - 13 nights
Testing :
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In depth blood work check
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In depth blood pressure check
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Arterial stiffness
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Cardiac evaluation
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DNA test
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DEXA scan
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Thyroid Ultrasound
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Gut microbiome analysis
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Continuous Glucose Monitoring
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Diagnosis of atherosclerosis
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Diagnosis of hepatic steatosis
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Telomere length test
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Mitochondrial activity test
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VO2 max
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Resting metabolic rate
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GAIT/biomecanical analysis
-
3D body scan
-
Posture analysis
-
Cognitive test
-
Nutrition Habits assessment
-
Sleep assessment
Therapies :
-
Infrared light session
-
Sauna
-
Breathing session
-
Customized PT session
-
Exercise with Oxygen therapy
-
Altitude Training
-
Cryotherapy
-
Hyperbaric Oxygen Chamber Therapy
-
Meditation protocol
-
Audiotherapy session
-
Body treatment at Guerlain Spa
-
Personalised nutrition plan
-
Yoga Session
-
Herbal infusions
-
This program is designed for individuals who approach longevity proactively and with commitment.
It is ideal for guests who wish to understand and actively influence the biological markers of aging, rather than respond to decline once it appears.
Advanced Longevity Immersion is for those who view longevity as a strategic investment — and who seek a scientifically guided, deeply personalised experience to support sustained vitality, performance, and quality of life over time.
Science. Personalisation. Luxury.
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Programs built from Europe’s most advanced diagnostics
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Treatments calibrated to your unique biology
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Interventions backed by clinical research, delivered with elegance
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Full alignment between medicine, movement, nutrition, sleep & mindset
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Discreet, world-class service at One&Only Aesthesis Athens

THE ASCEND TAILOR-MADE EXPERIENCE
For our most discerning guests, Ascend offers a program without limits — curated entirely around your biology, lifestyle, and objectives.
Using your Longevity Blueprint, our medical team designs a complete longevity, performance, and regeneration protocol tailored entirely to you.
No two Tailor-Made programs are alike — by design.
HEAR FROM OUR HAPPY GUESTS
“Use this space to share a testimonial quote about the business, its products or its services. Insert a quote from a real customer or client here to build trust and win over site visitors.”
—Jordan
HEAR FROM OUR HAPPY GUESTS
“Use this space to share a testimonial quote about the business, its products or its services. Insert a quote from a real customer or client here to build trust and win over site visitors.”
—Tara
HEAR FROM OUR HAPPY GUESTS
“Use this space to share a testimonial quote about the business, its products or its services. Insert a quote from a real customer or client here to build trust and win over site visitors.”
—Hannah


